Catalog Number | NSJ-BC-007 |
Category | TLR7/8 agonist |
Sub-Category | Vaccine adjuvants |
Therapeutic applications | Immune response modifier |
CAS No. | 2137880-92-1 |
Chemical Name | 4-(3-((4-Amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)methyl)phenyl)butan-2-one |
Chemical Formula | C25H28N4O |
Synonyms | IMQ |
Molecular Weight | 400.53 |
Reference | 1. Aichhorn, S, et al, A pH-sensitive Macromolecular Prodrug as TLR7/8 Targeting Immune Response Modifier Chem. Eur. J. 2017, 23, 17721-17726
2. Beesu, M, et al, Structure-based design of human TLR8-specific agonists with augmented potency and adjuvanticity, J. Med. Chem. 2015, 58, 7833–7849 |