Catalog Number | NSJ-BC-004 |
Category | TLR7/8 agonist |
Sub-Category | Vaccine adjuvants |
Therapeutic applications | Anticancer |
CAS No. | 144875-48-9 |
Chemical Name | 1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol |
Chemical Formula | C17H22N4O2 |
Synonyms | R-848; S 28463, Resquimod |
Molecular Weight | 314.39 |
Reference | 1. Smirnov, D. et al, Vaccine adjuvant activity of 3M-052: An imidazoquinoline designed for local activity without systemic cytokine induction Vaccine, 2011, 29, 5434-5442.
2. Lee, M. et al , Resiquimod, a TLR7/8 agonist, promotes differentiation of myeloid-derived suppressor cells into macrophages and dendritic cells, Arch. Pharm. Res. 2014, 37, 1234–1240. |