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1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol

1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol

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 Catalog Number NSJ-BC-004
Category TLR7/8 agonist
Sub-Category Vaccine adjuvants
Therapeutic applications Anticancer
CAS No. 144875-48-9
Chemical Name 1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
Chemical Formula C17H22N4O2
Synonyms R-848; S 28463, Resquimod
Molecular Weight 314.39
Reference 1. Smirnov, D. et al, Vaccine adjuvant activity of 3M-052: An imidazoquinoline designed for local activity without systemic cytokine induction Vaccine, 2011, 29, 5434-5442.

2. Lee, M. et al , Resiquimod, a TLR7/8 agonist, promotes differentiation of myeloid-derived suppressor cells into macrophages and dendritic cells, Arch. Pharm. Res. 2014, 37, 1234–1240.