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1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine

1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine

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 Catalog Number NSJ-BC-006
Category TLR7/8 agonist
Sub-Category Vaccine adjuvants
Therapeutic applications Anticancer
CAS No. 1258457-58-7
Chemical Name 1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine
Chemical Formula C22H25N5
Synonyms meta-IMDQ
Molecular Weight 359.48
Reference 1. Yoo, E, et al, Hyaluronic acid conjugates of TLR7/8 Agonists for targeted delivery to secondary lymphoid tissue Bioconjugate Chem. 2018, 29, 2741−2754.

2. Beesu, M, et al, Structure-based design of human TLR8-specific agonists with augmented potency and adjuvanticity, J. Med. Chem. 2015, 58, 7833–7849.