Catalog Number | NSJ-BC-006 |
Category | TLR7/8 agonist |
Sub-Category | Vaccine adjuvants |
Therapeutic applications | Anticancer |
CAS No. | 1258457-58-7 |
Chemical Name | 1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine |
Chemical Formula | C22H25N5 |
Synonyms | meta-IMDQ |
Molecular Weight | 359.48 |
Reference | 1. Yoo, E, et al, Hyaluronic acid conjugates of TLR7/8 Agonists for targeted delivery to secondary lymphoid tissue Bioconjugate Chem. 2018, 29, 2741−2754.
2. Beesu, M, et al, Structure-based design of human TLR8-specific agonists with augmented potency and adjuvanticity, J. Med. Chem. 2015, 58, 7833–7849. |