Catalog Number | NSJ-BC-005 |
Category | TLR7/8 agonist |
Sub-Category | Vaccine adjuvants |
Therapeutic applications | Anticancer |
CAS No. | 1258457-59-8 |
Chemical Name | 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine |
Chemical Formula | C22H25N5 |
Synonyms | IMDQ |
Molecular Weight | 359.48 |
Reference | 1. Yoo, E, et al, Hyaluronic acid conjugates of TLR7/8 agonists for targeted delivery to secondary lymphoid tissue, Bioconjugate Chem. 2018, 29, 2741−2754.
2. Vrieze, J. D. et al, Potent lymphatic translocation and spatial control over innate immune activation by polymer–lipid amphiphile conjugates of small-Molecule TLR7/8 agonists Angew. Chem. Int. Ed. 2019, 58, 15390 –15395. |